Learning Resource 05. The Learning Resource goal is to use the Internet and become independent of the textbook. It is a project in progress...
Ch. x Ch. x Ch. x




The Cell membrane







The scale figure is included to remind you about the level of scale of the structures we are discussing.






--- Cell Membrane ---


Living organisms are separated from the environment by a flexible sheet called the cell membrane (or plasma membrane).

Encloses the cell from its surrounding -- different composition compared to the surrounding

yet the cell can

--- eliminate waste
---
take up nutrients (& toxins & pollutants)


The cell membrane is primarily made of phospholipids, and is called the gatekeeper of the cell because it regulates what enters and leaves the cell. This is due to the nature of the components of the membrane.




The Phospholipids, e.g., the non-polar and hydrophobic tails directed inwards into the bilayer. Cholesterol is also an important chemical in the plasma membrane and its presence reduces the permeability. Certain molecules or ions can freely cross the plasma membrane through channel proteins. Glycoproteins, on the outside of the plasma membrane, determines a persons particular blood type.


Fluid and Mosaic Quality of the plasma membrane

Fluid in texture
Mosaic in composition






--- Membrane transport ---




1.
Diffusion. Passive transport -- does NOT require energy. Movement from a high concentration to a low concentration -- e.g., paint spreading in a bucket or water -- or -- transportation of oxygen into the body.

def. Diffusion: Net movement of molecules from a place of higher concentration, to a place of lower concentration (movement DOWN a concentration gradient)

2. Facilitated Diffusion. Passive transport helped with membrane proteins -- does NOT require energy. Movement from a high concentration to a low concentration -- e.g., nutrient transport through a membrane protein

3. Active transport. "Active" transport -- requires energy. Movement from a LOW concentration to a HIGH concentration -- e.g., sodium-potassium pump in the cell membrane.





--- Concentration Differentials ---



The maintenance of a normal water balance (osmotic pressure) is important for living organisms. Diffusion of water for this purpose takes place through the cell membrane -- a semi-permeable membrane.



def. Osmoregulation: The maintenance of an optimal and constant water balance (osmotic pressure) in the body of organisms living in hypertonic, hypotonic and terrestrial environments.
def. Osmosis: Diffusion (net movement of molecules from a place of higher concentration to a place of lower concentration) of water through a semi-permable membrane.
def. Osmotic Pressure: A measure of the tendency of a solution to take up water when separated from pure water by a semi-permeable membrane.



To understand this we need to understand the terminology, and compare differences between animal cells and plant cells.



1. Isotonic solutions

2. Hypotonic solutions

3. Hypertonic solutions







Water Balance in an animal cell




Example: Water balence in RBCs



1. ISOTONIC water solution (e.g., blood plasma compared to human cells)

Water flows across the membrane at the same rate

(NORMAL, STABLE)


2. HYPERTONIC water solution (e.g. ocean salt water comp. to human cells)

water flows out of the cell at a faster rate

(LOSS OF WATER, SHRIVEL, DIE)


3. HYPOTONIC water solution (e.g. pond fresh water comp. to human cells)
‡ water flows into the cell at a faster rate

(GAIN WATER, SWELL, BURST)



What is isotonic solutions can vary between different animals

e.g., Isotonic Salt Concentration in Humans -- 0.7% salt
Isotonic Salt Concentration in Jellyfish -- 3.5% salt
(same as the sea water)

Animals must live in an environment ISOTONIC to their cells, unless they have a method to balance water gain or water loss

-- OSMOREGULATION


An isotonic condition is the stable state in animal cells.






Water Balance in a plant cell







Plant cells depend on "turgor pressure". An hypotonic condition is the stable state in plant cells.







In review: In animal cells Isotonic conditions are normal, and in plant cells hypotonic conditions are normal...

1. Blood plasma (in human blood vessels) is _____ compared to a human red blood cell:

a. isotonic
b. hypotonic
c. hypertonic
d. hyposonic
e. hypersonic

2. Distilled water is _____ compared to human red blood cell:

a. isotonic
b. hypotonic
c. hypertonic
d. hyposonic
e. hypersonic

3. The outer plasma membrane that separates a cell from its environment:

a. nuclear membrane
b. cell wall
c. organelle
d. cell membrane
e. cell lining







- - - Khan Academy You Tube - - -

COMMENT ON THE YOUTUBE: we have a test tomorrow and i was really confused about? osmosis and diffusion. but now i understand it. thanks alot.







- - - Connecting the Concepts - - -

Our knowledge of the plasma membrane is important in understanding the diseases such as diabetes, cystic fibrosis, some cancers, and high cholesterol count. This is dependent on knowledge of the molecules that make up the cell.

(Source: Mader, S.S. 2010. Biology. Ed. 10. Used for educational purpose.)